Xenograft Tumor Models for Oncology Studies
MB Biosciences offer tumor cell line-derived xenograft (CDX) models, orthotopic mouse model and patient-derived tumor xenografts mouse models.
Tumor cell line derived tumor xenograft (CDX) models are widely used for preclinical test to evaluate the efficacy of anti-tumor therapeutics and study the mechanisms of action in the biologic processes in oncology. CDX models are established by inoculating variety of tumor cell lines into immunodeficient mice. The cells can be implanted subcutaneously, intravenously or orthotopically to induce tumors growth.
MB Biosciences Advantages
Highly experienced and skilled team
Covering a broad range of human tumor cells lines
Quick turnaround time
Providing customized services to meet your research need
Our full range of tumor cell lines is listed below. If you have any special requirements, please contact us; we are happy to work with you to develop a specific CDX model.
| Tumor Type | Cell Line |
|---|---|
| Bladder | SW780, |
| Brain | U87MG |
| Breast | MDA-MB-231, BT474, MCF-7, MDA-MB436, MDA-MB-368, ZR-75 |
| Colon | HCT116, HT29, SW-48 |
| Epidermoid Carcinoma | A431 |
| Esophageal | OE-33 |
| Gastric | N87, SNU-5 |
| Head and Neck | FaDu, CAL-27 |
| Leukemia | MV4-11, RS4;11, Kasumi-1, JURKAT, K-562, THP-1 |
| Liver | Hep3B, Hep G2, SK-HEP-1 |
| Lung (Non-small cell) | H460, A549, H1299, H1975, H23 |
| Lung (Small Cell) | H82, H1963, H727 |
| Melanoma | A375, HT-144 |
| Multiple Myeloma | RPMI 8226 |
| Osteosarcina | 143B, Saos-2 |
| Ovarian | OVCAR-3, SK-OV-3 |
| Pancreatic | MiaPaCa-2, BxPc-3, PANC1 |
| Prostate | DU145, PC3, PC-3M, LNCap, LNCaP, C4-2, C4-222Rv.1 |